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1.
Opt Express ; 19(5): 3825-34, 2011 Feb 28.
Artigo em Inglês | MEDLINE | ID: mdl-21369207

RESUMO

A novel integrated optical source capable of emitting faint pulses with different polarization states and with different intensity levels at 100 MHz has been developed. The source relies on a single laser diode followed by four semiconductor optical amplifiers and thin film polarizers, connected through a fiber network. The use of a single laser ensures high level of indistinguishability in time and spectrum of the pulses for the four different polarizations and three different levels of intensity. The applicability of the source is demonstrated in the lab through a free space quantum key distribution experiment which makes use of the decoy state BB84 protocol. We achieved a lower bound secure key rate of the order of 3.64 Mbps and a quantum bit error ratio as low as 1.14×10⁻² while the lower bound secure key rate became 187 bps for an equivalent attenuation of 35 dB. To our knowledge, this is the fastest polarization encoded QKD system which has been reported so far. The performance, reduced size, low power consumption and the fact that the components used can be space qualified make the source particularly suitable for secure satellite communication.


Assuntos
Amplificadores Eletrônicos , Tecnologia de Fibra Óptica/instrumentação , Lasers de Estado Sólido , Iluminação/instrumentação , Refratometria/instrumentação , Medidas de Segurança , Desenho Assistido por Computador , Desenho de Equipamento , Análise de Falha de Equipamento
2.
Farm. hosp ; 34(6): 293-297, nov.-dic. 2010. ilus, tab
Artigo em Inglês | IBECS | ID: ibc-107083

RESUMO

Objective Two carvedilol aqueous solutions and one carvedilol aqueous suspension for paediatric oral use (1mg/ml) were studied to determine their stability. Method All samples were stored at 4, 25 and 40°C. Carvedilol content of each of the three formulations was tested using high performance liquid chromatography (HPLC). Each sample was analysed in triplicate at 0, 3, 7, 14, 28 and 56 days. Results Carvedilol stayed stable in the acidic aqueous solution at the three different temperatures during the 56 days of the study. In the alkaline solution, carvedilol was stable during 56 days at 25°C, but only 28 days at 4 and 40°C. In the aqueous suspension, carvedilol was stable during 56 days at 4 and 25°C, but only 28 days at 40°C.ConclusionsAll the formulations that were tested can be stored at 25°C for at least 56 days(AU)


Objetivo Se estudió la estabilidad de carvedilol (1mg/ml) en 2 soluciones acuosas y una suspensión acuosa para uso pediátrico. Método Las formulaciones fueron almacenadas a 4, 25 y 40°C. El contenido de carvedilol de cada una de las 3 formulaciones fue analizado por cromatografía líquida de alta eficacia (HPLC). Cada muestra fue analizada por triplicado a tiempos 0, 3, 7, 14, 28 y 56 días. Resultados Carvedilol se mantuvo estable en la solución acuosa de pH ácido durante los 56 días del ensayo a las 3 temperaturas estudiadas. En la solución alcalina fue estable 56 días a 25°C, pero sólo 28 días a 4 y 40°C. En la suspensión acuosa carvedilol fue estable 56 días a 4 y 25°C, y sólo 28 días a 40°C.ConclusionesTodas las formulaciones ensayadas pueden ser conservadas a 25°C al menos por un período de 56 días (AU)


Assuntos
Humanos , Criança , Carbazóis/farmacologia , Propanolaminas/farmacologia , Estabilidade de Medicamentos , Soluções Farmacêuticas , Propanolaminas/administração & dosagem , Suspensões
3.
Farm Hosp ; 34(6): 293-7, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20418137

RESUMO

OBJECTIVE: Two carvedilol aqueous solutions and one carvedilol aqueous suspension for paediatric oral use (1mg/ml) were studied to determine their stability. METHOD: All samples were stored at 4, 25 and 40°C. Carvedilol content of each of the three formulations was tested using high performance liquid chromatography (HPLC). Each sample was analysed in triplicate at 0, 3, 7, 14, 28 and 56 days. RESULTS: Carvedilol stayed stable in the acidic aqueous solution at the three different temperatures during the 56 days of the study. In the alkaline solution, carvedilol was stable during 56 days at 25°C, but only 28 days at 4 and 40°C. In the aqueous suspension, carvedilol was stable during 56 days at 4 and 25°C, but only 28 days at 40°C. CONCLUSIONS: All the formulations that were tested can be stored at 25°C for at least 56 days.


Assuntos
Carbazóis/farmacologia , Propanolaminas/farmacologia , Administração Oral , Carbazóis/administração & dosagem , Carvedilol , Criança , Estabilidade de Medicamentos , Humanos , Soluções Farmacêuticas , Propanolaminas/administração & dosagem , Suspensões
4.
Conscious Cogn ; 17(1): 267-75, 2008 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17616470

RESUMO

The present work investigates whether the hemispheric processing of both verbal and emotional stimuli, studied by means of a dichotic listening task, differs between normal high and low dissociators as assessed by the Dissociative Experiences Scale (DES; Bernstein & Putnam (1986). Development, reliability and validity of a dissociation scale. Journal of Nervous and Mental Disease, 174(2), 727-735). Two groups of subjects (50 high and 50 low dissociators), participated in the experiment. The task consisted in identifying both verbal and emotional stimulus-targets, respectively, on successive sessions. Reaction time and response accuracy were registered and analysed using ANOVA (Analysis of Variance). The interaction between stimuli (verbal, emotional), channel (right ear, left ear), and dissociation level (high, low) reached statistical significance in terms of accuracy measures (d': F(1,98)=4.75; p<.05). Both high and low dissociators exhibited the expected right ear advantage (REA effect) on verbal targets. On the other hand, whereas low dissociators exhibited the expected left ear advantage (LEA effect) on emotional targets, high dissociators failed to follow this typical pattern of hemispheric asymmetry: both hemispheres exhibited similar performances. These results confirm the hypothesis that dissociation is related to changes in hemispheric processing, specifically of emotional information.


Assuntos
Transtornos Dissociativos/psicologia , Emoções , Lateralidade Funcional , Percepção da Fala , Adulto , Análise de Variância , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Proibitinas , Tempo de Reação
5.
J Microsc ; 218(Pt 2): 193-7, 2005 May.
Artigo em Inglês | MEDLINE | ID: mdl-15857381

RESUMO

Usually, the calibration process for three-dimensional microscopy involves the use of a reference flat surface. The random fluctuations of the topographic image for this reference surface are used for determining the uncertainty of the microscope. When the sample material or the measuring conditions of the microscope are modified (such as the objective used in a confocal microscope, or the tip in an atomic force microscope), the measuring conditions vary and thus a new calibration is required. In this work, a technique based on spatial statistics methods (more specifically, the variogram function) is proposed to determine accurately the standard deviation for three-dimensional microscopy that does not require a reference flat surface and therefore eliminates the need for a previous calibration process of this parameter.

6.
Patol. apar. locomot. Fund. Mapfre Med ; 3(1): 55-63, ene.-mar. 2005. ilus, graf
Artigo em Es | IBECS | ID: ibc-047410

RESUMO

Introducción: El quitosano es un material potencialmenteútil en el transporte de células humanas.Objetivos: Comparar los distintos materiales a base de quitosanopreparados para su uso como biomateriales potenciales.Materiales y métodos: Tras la preparación y esterilizaciónde diferentes formas de distintos materiales a base de quitosanose procede a su adición a un cultivo primario de osteoblastoshumanos. Mediante distintas técnicas se analiza la superficie,homogeneidad, hinchamiento y la penetración en elbiomaterial de las células cultivadas.Resultados: Se ha encontrado penetrabilidad osteoblásticaasí como crecimiento superficial en distintos materiales dequitosano


Introduction: Chitosan is a potentially human cells carrieruseful material.Objectives: To compare several based-on chitosan materialsin several chitosan preparations or their use as potentialbiomaterials by human cultured osteoblasts.Material and methods: Different chitosan forms wereprepared and sterilized. Then they were added to a primaryhuman osteoblasts culture. Surface, homogeneity swellingand osteoblasts penetration into the biomaterial was analyzedusing several techniques.Results: Osteoblastic penetrability was found. Surfacegrowing on differents chitosan materials could be demonstrated


Assuntos
Materiais Biocompatíveis/análise , Osteoblastos/fisiologia , Quitina/uso terapêutico , Substitutos Ósseos/análise , Regeneração Óssea/fisiologia
7.
Patol. apar. locomot. Fund. Mapfre Med ; 3(2): 144-151, abr.-jun. 2005. ilus, tab
Artigo em Es | IBECS | ID: ibc-047418

RESUMO

INTRODUCCIÓN. El quitosano es un material potencialmenteútil en el transporte, fijación y desarrollo de osteoblastosOBJETIVOS. Analizar la estructura y distribuciónde poros en materiales con base quitosano parajustificar la selección de materiales estructuralmente compatiblescon el transporte, fijación y desarrollo de osteoblastos.RESULTADOS. Se pone de manifiesto la dependenciadel tamaño de poro con el contenido de quitosanoy, también se induce un posible modelo gráfico de distribuciónestructural de los poros que justifica la compatibilidadde los resultados micrométricos con los de medida dela porosidad por difusión de vapor de mercurio


INTRODUCTION. Chitosan is a potentially useful materialfor the transportation, fixation and development ofosteoblasts. OBJECTIVES. To analize the structure and distributionof pores in chitosan-based materials in order tojustify the selection of structurally compatible materialswith the transportation, fixation and development of osteoblasts.human cells carrier human cells carrier RESULTS.It has been shown the dependency of the pore sizewith the chitosan and, also, it is seen a possible graphicmodel of structural distribution of pores that justifies thecompatibility of the micrometrical results with those measuredby mercury vapor diffusion


Assuntos
Quitina/uso terapêutico , Osteoblastos/ultraestrutura , Teste de Materiais/métodos , Microscopia Confocal , Porosidade , Substitutos Ósseos/análise
8.
J Opt Soc Am A Opt Image Sci Vis ; 18(7): 1452-9, 2001 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-11444535

RESUMO

We present a new algorithm to calculate the optical imbalances and differential prismatic effects that appear when two eyes look at an object through correcting eyeglasses. These are important magnitudes in ophthalmic optics because large amounts of them will disturb the binocular vision of the spectacle wearer. As a practical application of our algorithm, the distribution of optical imbalances and differential prismatic powers for a pair of progressive addition lenses has been calculated, and we obtain information about the effects of this kind of lens on the binocular vision of the wearer.


Assuntos
Algoritmos , Óculos , Modelos Teóricos , Visão Binocular , Humanos
9.
Appl Opt ; 40(4): 527-32, 2001 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-18357027

RESUMO

The variation of the optical properties of porous Vycor glass (Corning, Model 7930) under different relative-humidity conditions was studied. The adsorption of water into the glass pores was investigated with spectroscopic ellipsometry. The change of the refractive index was Deltan approximately 0.04 between 5% and 90% relative humidity. A linear relation between the ellipsometer parameter tan Psi, the amount of water adsorbed in the glass pores, and information about the pore-size distributions was established. The results are in accord with the values obtained from N2 isotherms, transmission electron microscope micrographs, and the manufacturer's specifications (radius of approximately 20 A). The possibility of using this material as a transducer for implementation in a fiber-optic sensor to measure humidity was evaluated.

10.
Appl Opt ; 40(4): 533-7, 2001 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-18357028

RESUMO

The application of LED technology to fields such as alphanumerical displays and traffic control is continuously increasing. Because the technology is used outdoors, it must be able to operate under various environmental conditions. Like all semiconductor devices, LED's have properties that change with temperature. We propose a semiempirical model, based on semiconductor solid-state theory, that predicts the changes in the emission spectrum including the effect of temperature changes on the optical properties of the LED, within a range appropriate for outdoor applications (0-40 degrees C). This model permits us to evaluate the changes in the output flux and the chromaticity coordinates of the LED. We checked this model with seven different LED's.

11.
Opt Express ; 8(12): 649-54, 2001 Jun 02.
Artigo em Inglês | MEDLINE | ID: mdl-19421254

RESUMO

We have extended the use of shadow Moiré technique to be implemented in simple curved surfaces by using a flexible grating. Dynamic visual inspection of surface micro-damages is significantly favored by the use of well adapted pliable gratings compared to the use of flat reference gratings. The experimental set-up consists of a plastic foil with a printed Ronchi grating stretched between three points which adapts to any cylindrical or conical convex surface independently of the relative orientation grating/surface. Static quantification of defects profiles is also possible with an attached CCD camera. Visual detection of defects in the range of ~30 microm in depth is obtainable.

12.
Ophthalmic Physiol Opt ; 20(6): 473-9, 2000 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11127127

RESUMO

The warpage of a set of six hard resin spherical lenses was measured when they were compressed by means of the tangential force exerted by a metal frame. The technique employed to measure the lenses improves over previous work both because greater precision is achieved, and because radii of curvature are measured in two perpendicular meridians. In this work, a representative sample of lenses has been used in order to test the way in which deformation depends on lens power and base. It is found that the induced warpage is enough to move the tested lenses between different base families, spoiling the initial design of the manufacturer.


Assuntos
Óculos/normas , Força Compressiva/fisiologia , Humanos , Pressão , Estresse Mecânico
13.
J Opt Soc Am A Opt Image Sci Vis ; 17(7): 1231-40, 2000 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-10883975

RESUMO

It is a well-known fact that one grating can act as an imaging element for another grating when the first is illuminated with an extended monochromatic light source. The conditions for image formation in such a system are studied when the finite size and position of the broad light source are considered. From the presented analysis, expressions for the location and the depth of focus of such images can be derived.

14.
Appl Opt ; 39(4): 539-45, 2000 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-18337923

RESUMO

In industrial applications of thin metallic wires it is important to characterize the surface defects of the wires. We present an optical technique for the automatic detection of surface defects on thin metallic wires (diameters, 50-2000 microm) that can be used in on-line systems for surface quality control. This technique is based on the intensity variations on the scattered cone generated when the wire is illuminated with a beam at oblique incidence. Our results are compared with those obtained by atomic-force microscopy and scanning-electron microscopy.

15.
Appl Opt ; 39(22): 3805-13, 2000 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-18349956

RESUMO

Reflection optical encoders are studied as three-grating moiré systems. An analysis is made of the differences that may appear between it and the standard case in which an optical encoder is regarded as a two-grating system.

16.
Appl Opt ; 39(23): 4098-106, 2000 Aug 10.
Artigo em Inglês | MEDLINE | ID: mdl-18349991

RESUMO

A histogram-based technique for robust contrast measurement is proposed. The method is based on fitting the histogram of the measured image to the histogram of a model function, and it can be used for contrast determination in fringe patterns. Simulated and experimental results are presented.

17.
Appl Opt ; 38(7): 1133-8, 1999 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-18305722

RESUMO

A planar optical array is presented that provides a selective concentration of the light incident upon the system onto a given area. Several alternative designs are analyzed and explained geometrically. The photometric calculation is presented for three different levels of approximation. A prototype of the proposed system is tested, showing good accordance with the theoretical predictions.

18.
Appl Opt ; 38(25): 5267-71, 1999 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-18324027

RESUMO

A fiber-optic sensor based on surface-plasmon resonance for the determination of the refractive index is used for measuring the degree of salinity of water. The transducing element consists of a multilayer structure deposited on a side-polished monomode optical fiber. Measuring the attenuation of the power transmitted by the fiber shows that a linear relation with the refractive index of the outer medium of the structure is obtained. The system is characterized by use of a varying refractive index obtained with a mixture of water and ethylene glycol. Experimental results show that the sensor can be used as a salinity-degree measurement device with environmental applications.

19.
Appl Opt ; 38(25): 5429-32, 1999 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-18324049

RESUMO

Rough surfaces in translucent protective sheets are used in imaging systems, such as displays, to decrease specular reflections of external sources. However, they modify the quality of the images formed by transmission. Using a geometric approximation, we have modeled the behavior of rough surfaces in imaging systems. This model provides an analytical expression for the modulation transfer function of rough surfaces.

20.
Ophthalmic Physiol Opt ; 18(6): 514-20, 1998 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-10070546

RESUMO

A generalization of the Prentice's law is presented in this paper. The idea consists of removing some (but not all) of the approximations that comprise the paraxial approach. In that way, we obtain a new formulation that permits us to compute the prismatic power of a lens made up of arbitrary refracting surfaces, and to improve the precision obtained by Prentice's law when applied to monofocal lenses. The resulting formalism is simple and manageable and its derivation leads us to a precise definition of the local dioptric power matrix, introduced in a previous paper, as well as a better understanding of the same.


Assuntos
Cristalino/fisiologia , Refração Ocular/fisiologia , Humanos , Matemática , Óptica e Fotônica
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